Inscripta is working to develop a full suite of gene-editing tools (reagents, software and instruments) to increase the efficiency and speed of CRISPR-based gene-editing

The US-based gene-editing technology company Inscripta has announced that it has raised additional $20 million in its previously declared Series C financing. The new funding, which comes from existing investors, adds to the $85.5 million financing that the company announced in 2018. The total amount raised now stands at $105.5 million.

According to the press release by Inscripta, the existing investors are Foresite, MLS Capital, Venrock, NanoDimension, Paladin Capital Group and Mérieux Développement. Inscripta is working to develop a full suite of gene-editing tools (reagents, software and instruments) to increase the efficiency and speed of CRISPR-based gene-editing.

The tools being developed by Inscripta include CRISPR enzyme family, called MADzymes; custom nucleases for commercial partners and researchers; and a full suite of gene-editing tools (reagents, software and instruments).

John Stuelpnagel, Chairman, Board of Directors, Inscripta, has reportedly said that researchers need a scale transformation to make gene editing efforts more useful and informative.

Reportedly, Inscripta had announced the broad adoption of MAD7 in December 2018. MAD7 is a proprietary CRISPR enzyme which has been offered to academic and commercial researchers without any upfront licensing fees or “reach-through royalties” on discoveries made using the technology.

For the record, MADzymes have different cut efficiencies, different PAM recognition sequences, different enzyme kinetics and reduced sizes. The first enzyme MAD7’s gene editing systems were patented recently. The enzyme is reportedly effective in microbial as well as mammalian systems. The robust editing activities have been shown by MAD7 in prokaryotic as well as eukaryotic microbes.

For the uninitiated, Colorado-based Inscripta is a gene-editing technology company which creates tools to revolutionize human life. The company works to provide control to researchers for cutting edge, single cell engineering.