Myriad’s myChoice CDx bags FDA approval for treatment with Zejula
  Author: Mateen Dalal

Ovarian cancer is termed as fifth most common cause of cancer-related death among women in the U.S. It can mostly be treated by surgery or chemotherapy; however, several biotech companies are now making some groun...

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FDA approves AstraZeneca’s Farxiga for treating type 2 diabetes
  Author: Nikita Chaurasia

Type-2 diabetes is classified as a chronic condition that impacts the body’s way of processing blood sugar or glucose. Currently, the condition can be regulated using exercise, diet, insulin therapy and medicatio...

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Eli Lilly’s Phase 3 SEQUOIA trial fails to meet primary endpoint
  Author: Mateen Dalal

Metastatic pancreatic cancer (MPC) is one of the most fatal cancers in the world. Pancreatic cancer is slated to be the third leading cause of cancer death in the U.S. and is expected to become the second leading cause...

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Replimune gives an update on RP1 Clinical Development Program in CSCC
  Author: Mateen Dalal

Cutaneous squamous cell carcinoma (CSCC) is the second most common form of skin cancer caused because of the uncontrolled growth of abnormal squamous cells. Currently, Libtayo is the only approved treatment in the Braz...

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Kyowa Kirin’s NOURIANZ™ bags FDA nod for sale in the U.S.
  Author: Mateen Dalal

Parkinson’s Disease is a progressive nervous system disorder that hampers the movement of the body by causing stiffness or slowness. Currently there are no definitive treatments for this clinical condit...

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GE Healthcare and Telix make some strides in prostate cancer imaging
  Author: Mateen Dalal

Prostate cancer is one of the leading causes of deaths among men in the U.S. On an average, 1 out of 9 men are diagnosed with prostate cancer in their lifetime. Currently, there are several treatments which can pr...

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Pfizer reveals positive data from Phase 3 trial of ABROCITINIB
  Author: Mateen Dalal

Atopic Dermatitis (AD) is a chronic skin disease characterized by skin barrier defects and inflammation. It results in itching, induration (hardening)/papulation (formulation of papules), and oozing/crusting and affect...

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Avacta inks Collaboration and Option Agreement with ADC Therapeutics
  Author: Mateen Dalal

Among the most vital treatment breakthrough for cancer patients are therapies that targeted the site of tumors and regimens with novel combinatio...

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Annexon Biosciences reveals positive data from ANX007 Phase 1b trial
  Author: Mateen Dalal

Glaucoma is an eye condition in which fluid pressure builds up within the eye affecting optic nerves. If not treated, a Glaucoma patient might lose partial vision or even go blind. The disease mostly occurs in older ad...

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FDA awards $15 million through 12 grants to fund new clinical trials
  Author: Mateen Dalal

There is a substantial rise in the pharmaceutical firms conducting clinical trials to discover new therapies for a plethora of rare diseases. To encourage pharmaceutical firms to intensify their research efforts and to...

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Nicox announces topline results from Glaucoma Dolomites Phase 2 Trial
  Author: Mateen Dalal

Glaucoma is a disease that damages a patient’s optic nerve and can eventually lead to blindness if not treated on time. It is currently considered to be the third leading cause of irreversible blindness worldwide...

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iCAD exhibits ProFound AI™ platform for DBT at the EUSOBI in Budapest
  Author: Mateen Dalal

Breast cancer is one of the most prominent cancer types that can occur in women. Though treatment options depend on the stage of the disease, it can be addressed successfully if diagnosed and treated early. Various med...

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ImmunoGen presents data from FORWARD II Triplet Cohort at ESMO
  Author: Mateen Dalal

Ovarian cancer occurs when cells in the ovary start to mutate abnormally, further forming a tumor. At late stages, ovarian cancer can become difficult to treat and could also be fatal to patient. Several pharmaceu...

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GlaxoSmithKline presents the PRIMA study for first-line ovarian cancer
  Author: Mateen Dalal

The treatment graph for one of the most fatal ailments of the 21st century, the dreaded ‘cancer’, seems to be on the verge of witnessing yet another variable addition. In what may seem as yet ano...

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Herantis Pharma releases update on timeline of its ongoing CDNF trial
  Author: Nikita Chaurasia

Parkinson's disease (PD) is an incurable, progressive neurodegenerative disease which is caused by the death of dopaminergic neurons in the midbrain. With medication, motor symptoms can be treated but it is impossi...

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Incyte treats first patient in its Phase 3 ruxolitinib clinical trial
  Author: Mateen Dalal

Vitiligo is a common disease that causes the patient to lose skin color in random blotches. The disease can affect any body part, even affecting the inside of the patient’s mouth and hair. There are some tre...

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Galapagos begins Phase 1 trial for second generation Toledo compound
  Author: Mateen Dalal

Cases of inflammatory diseases are expected to increase in the near future, which is a major concern for people across the world. Various pharmaceutical companies as well as medical research organizations are increasin...

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PhoenixMD gets FDA nod for Phase 1/1b clinical trial of PMD-026
  Author: Mateen Dalal

Breast cancer is the second most common cause of death among women. With rising cases of breast cancer recorded worldwide, the need for developing an effective therapy has become a priority for many pharmaceutical...

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GenSight reveals positive results from RESCUE Phase III trial of GS010
  Author: Mateen Dalal

Leber Hereditary Optic Neuropathy (LHON) is a hereditary form of vision loss that usually begins at teenage or in the early twenties. With few rare cases likely to occur in late adulthood or early childhood, vario...

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BeiGene announces clinical results of anti-PD-1 antibody- Tislelizumab
  Author: Mateen Dalal

With novel clinical trials, organizations across the world are developing new therapies and next-generation treatment for targeting fatal diseases such as cancer. The result of such clinical trials can aid the improvem...

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Lineage Cell Therapeutics’ Renevia bags CE Mark Approval for EU market
  Author: Mateen Dalal

Aesthetic medicine is increasingly being used for the treatment of physical impairments such as skin discoloration, excessive fat, scars, skin laxity, wrinkles, cellulite, and liver spots. Customer are seen demanding f...

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Cipla and PULM dose first patient with Pulmazole in Phase 2 ABPA trial
  Author: Mateen Dalal

There is a substantial rise in the number of people affected with pulmonary diseases like asthma. Various pharmaceutical companies in the world are combining their capabilities to find treatments for serious pulmonary ...

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AC Immune gets milestone payment to initiate Phase 2 trial of PI-2620
  Author: Mateen Dalal

As cases of neurodegenerative diseases like Alzheimer’s and Parkinson’s are on a rise, biopharmaceutical firms are actively engaging in developing new clinical drugs. Companies are also gaining increased fu...

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AstraZenecas Farxiga gets fast track status to treat heart failure
  Author: Mateen Dalal

With heart related issues and number of people diagnosed with heart failure increasing substantially, the need to find a solution to this problem is growing considerably. Advanced technology, equipment and pharmaceutic...

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Patient data from Oncopeptides’ Phase 2 trial to be showcased at IMW
  Author: Mateen Dalal

Patients having Relapsed-refractory multiple myeloma (RRMM) along with extramedullary disease (EMD) will be treated by Oncopeptides AB. In the comp...

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Vertex- Scottish govt. sign cystic fibrosis treatment access contract
  Author: Mateen Dalal

As part of the 5-year agreement, Vertex will also be collecting real world data on these medicines. Vertex Pharmaceuticals Incorporated has reportedly announced tha...

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Grünenthal and Mesoblast partner to develop innovative cell therapy
  Author: Mateen Dalal

Grünenthal will own the exclusive commercialization rights of allogeneic cell therapy candidate MPC-06-ID in Latin America and Europe. Grünenthal, a pharm...

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Medtronic’s IN.PACT AV Access trial meets effectiveness endpoints
  Author: Mateen Dalal

IN.PACT AV DCB showed encouraging results in the treatment of AV Fistulae Lesions in Renal Disease Patients at its last stage. Medtronic plc, one of the world&rsquo...

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Oxurion concludes enrollment of patients for THR-687 Phase 1 trial
  Author: Nikita Chaurasia

12 patients with DME have enrolled into the study.   The results for the Phase 1 trial will be out by the end of 2019. ...

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The Medicines Company declares positive results from Inclisiran trial
  Author: Nikita Chaurasia

The ORION-11 trial of inclisiran sodium 300 mg reached all secondary and primary endpoints with efficacy that is consistent with the findings from Phase 2 and 1 trials.   ...

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STALICLA completes pre-IND meet with FDA on STP1 for patients with ASD
  Author: Nikita Chaurasia

Atrium Spectrum Disorder (ASD) affects 1 in 59 school children of 8-years in the United States. It is a common neurodevelopmental disorder, with a higher level of heterogeneity.  ...

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Fitbit to support Singapore’s public health and smart nation programs
  Author: Mateen Dalal

Health population initiatives will be powered by Fitbit wearable devices and new Premium service Fitbit Inc., a San Francisco based tech company, has announced that...

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Mallinckrodt states positive results of Terlipressin in HRS-1 patients
  Author: Nikita Chaurasia

The company announced positive results from its Phase 3 CONFIRM trial of terlipressin in Hepatorenal Syndrome Type 1. The study verified HRS-1 reve...

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Sonnet to acquire Relief Therapeutics to develop atexakin alfa
  Author: Mateen Dalal

Sonnet proposes to pay 7,111,947 common shares and outstanding common stocks to Relief Therapeutics. Sonnet BioTherapeutics, Inc., a biotechnology company that deve...

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Bayer buys BlueRock Therapeutics, marks stance cell therapy space
  Author: Mateen Dalal

Versant Ventures’ portfolio company, Bluerock Therapeutics acquired by Bayer AG for approximately USD 1 billion. This acquisition represents ...

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Opthea unveils favorable results from Phase 2b wet AMD clinical trial
  Author: Mateen Dalal

Stable vision was achieved in 99.2% of subjects under the OPT-302 (2.0 mg) combination treatment, compared to 96.7% from the Lucentis control group at primary endpoint ...

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Eloxx Pharmaceuticals initiates Phase 2 clinical trial for ELX-02
  Author: Mateen Dalal

Six patients will be registered for the trial and will be treated with ELX-02 for four weeks with three rising dose levels. Eloxx Pharmaceuticals, Inc., an American...

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Squarex unveils Phase 2 results of SQX770 in recurrent herpes labialis
  Author: Mateen Dalal

The study involved around 139 subjects who had reported four or more episodes of herpes labialis in the past 12 months Squarex, a clinical-stage pharmaceutical comp...

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Genentech’s Tecentriq® plus chemotherapy helps reduce risk of ABC
  Author: Mateen Dalal

Data will be demonstrated at an upcoming medical meeting and shared with health authorities globally, including the U.S. FDA (Food and Drug Administration). Genentech, a subsidiary ...

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Brainscope declares to have surpassed primary endpoints in new study
  Author: Mateen Dalal

Brainscope has announced the successful completion of its nearly five year research contract with United States Department of Defense. The contract worth $9.9 million was to support the development and validation of an...

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Oyster Point begins enrolment for Phase 3 ONSET-2 study of nasal spray
  Author: Mateen Dalal

The trial is designed to assess the efficacy and safety of OC-01 for treating dry eye disease Reports confirm that Oyster Point Pharma, a clinical-stage biopharmac...

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Ligand buys AB Initio Biotherapeutics in a $12m cash transaction
  Author: Mateen Dalal

Ligand is eligible to receive royalties and milestones depending on potential future sales Ligand Pharmaceuticals Incorporated, a biopharmaceutical company focused ...

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Canopy Rivers’ joint venture awarded Health Canada cultivation license
  Author: Mateen Dalal

PharmHouse’s greenhouse facility in Ontario is reportedly one of the largest in the world Canopy Rivers Inc, Canopy Growth Corp’s venture capital arm, h...

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Detraxi to develop a new solution to reduce global blood shortages
  Author: Nikita Chaurasia

High income-growth countries like China will be the key recipient of the Detraxi biotechnology. Detraxi, a biotechnology company, is reportedly planning to develop ...

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LifeMax certified for treating Netherton Syndrome with LM-030
  Author: Nikita Chaurasia

LifeMax Laboratories Inc a subsidiary of LifeMax Healthcare International Corporation, recently announced that a Novartis licensed investigational therapy, LM-030, has been granted pediatric disease designation by the FD...

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Athira Pharma presents initial results from phase 1 trial of NDX-1017
  Author: Mateen Dalal

The company has been looking forward to initiate larger phase 2 trials. The clinical-stage company Athira Pharma, Inc. has reportedly announced preliminary data fro...

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Ascentage Pharma declares first patient dosed in APG-2575 trial
  Author: Nikita Chaurasia

APG-2575 created by Ascentage Pharma is one of the rare Bcl-2 selective inhibitors in active clinical studies apart from Venetoclax. Ascentage Pharma has repor...

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MediciNova confirms Phase 3 trial of ibudilast in progressive MS
  Author: Mateen Dalal

Ibudilast could be the best-in-disease drug for MS patients with unmet medical needs MediciNova, Inc., a biopharmaceutical company that develops novel therapeutics ...

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CMIC becomes Align Clinical CRO member to enhance trial partnerships
  Author: Mateen Dalal

The teaming up of CMIC with other companies will improve the collaboration and execution of clinical studies CMIC Group, a leading Japanese Contract Research Organization (CRO) that provides complete range of pharmaceutica...

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uniQure unveils Phase IIb study data of AMT-060 & AMT-061 therapy
  Author: Mateen Dalal

The data validates AMT-061 to be well-tolerated and capable of increasing FIX activity to normal in patients with hemophilia B. Renowned gene therapy firm, uniQure ...

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Cantargia confirms enrollment in Phase IIa trial for CAN04 monotherapy
  Author: Mateen Dalal

All the 20 patients for the monotherapy arm of the trial have begun treatment with 10 mg/kg dosage level Swedish biotech firm Cantargia has reportedly announced ful...

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Gilead plans to submit New Drug Application for Filgotinib to USFDA
  Author: Nikita Chaurasia

Gilead Sciences, Inc., a biotechnology company recently provided an update about the investigational- filgotinib, selective JAK1 inhibitor, at a pre-NDA (New Drug Application) meeting with the USFDA, cite sources. ...

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PeptiDream and Novartis to join forces on new peptide drug conjugate
  Author: Mateen Dalal

The partnership will bring the best first-in-class therapeutics and diagnostics for patients around the world PeptiDream, a public biopharmaceutical company that is...

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AbbVie acquires Allergan for $63B foreseeing Humira patent expiration
  Author: Mateen Dalal

American biopharmaceutical firm AbbVie Inc has reportedly announced its decision to acquire Botox-maker Allergan Plc in a $63 billion deal. Apparently, this move would hand over the...

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Applied Therapeutics unveils Phase 1/2 trial of Galactosemia treatment
  Author: Mateen Dalal

Galactosemia patients are in urgent need of treatment options and the company is committed to advancing AT-007 through clinical development Reports confirm that App...

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RIBOMIC confirms positive results from SUSHI study in wet AMD patients
  Author: Mateen Dalal

Phase 1/2a trial of RBM-007 was successfully conducted, yielding top-line results   Seven out of nine subjects showed a considerable im...

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Editas test CRISPR to treat beta-thalassemia & sickle cell disease
  Author: Nikita Chaurasia

Editas Medicine Inc., a U.S.-based pharmaceutical company recently announced results from trial of two different CRISPR-Cas9 genome editing strategies, one targeting the beta-globin locus and the other targeting the er...

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Hemispherx treats first patient in clinical trial of Ampligen
  Author: Nikita Chaurasia

Hemispherx Biopharma Inc., a US-based biopharmaceutical company recently announced having treated its first patient with Ampligen in combination with Cisplatin & Pembrolizumab, in a phase 2 ovarian cancer clinical ...

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Homology Medicines initiates Phase 1/2 trial for PKU gene therapy
  Author: Mateen Dalal

The firm’s drug (HMI-102) is expected to be the first gene therapy candidate for phenylketonuria (PKU) to enter clinics. Genetic drug maker, Homology Medicine...

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Medtronic commences pivotal trial for Next-Generation CGM sensor
  Author: Mateen Dalal

Next-generation Guardian CGM is designed to lower sensor calibrations, improve and refine the accuracy and the overall performance of the system World’s large...

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Cellenkos to test CK0801 for bone marrow failure syndromes treatment
  Author: Mateen Dalal

Cellenkos Inc., an early stage clinical biotechnology company recently announced initiation of Phase 1 clinical trial of CK0801 for treatment of bone marrow failure syndromes, including primary myelofibrosis, hypoplast...

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Sanofi unveils Phase 3 trial results of isatuximab combination therapy
  Author: Mateen Dalal

The French multinational pharmaceutical company Sanofi has reportedly announced crucial Phase 3 ICARIA-MM trial results which revealed that isatuximab aided with dexamethasone and pomalidomide (isatuximab combination t...

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Moderna announces data from Phase 1 mRNA cancer vaccine study
  Author: Nikita Chaurasia

The data revealed Moderna’s mRNA personalized cancer vaccine (PCV) mRNA-4157 to be well-tolerated at all tested doses and elicited neoantigen-specific T-cell responses. ...

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Novartis unveils positive Phase III trial data for asthma treatment
  Author: Mateen Dalal

Novartis has recently unveiled the first clinical trial results from the phase III PLATINUM clinical development program evaluating the efficacy and safety of QMF149, which is an investigational, once a day, fixed dose...

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Mesoblast submits BLA for remestemcel-L to treat aGVHD in children
  Author: Nikita Chaurasia

Mesoblast Limited has reportedly filed a rolling submission for Biologics License Application with the U.S Food and Drug Administration for remestemcel-L to treat steroid-refractory acute graft versus host disease in c...

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Rexgenero expands manufacturing of cell-based CLI therapy REX-001
  Author: Nikita Chaurasia

A regenerative medicine company Rexgenero, creating advanced cell-based therapies for the treatment of critical limb ischaemia, has reportedly expanded the production of its lead development therapy REX-001 by partneri...

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Eli Lilly’s mirikizumab scores positive data in Phase II Crohn’s study
  Author: Mateen Dalal

The company plans to initiate Phase III trials to assess mirikizumab’s benefit-risk profile to cure Crohn’s disease. U.S. pharma giant, Eli Lilly and Co...

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Merck to acquire cancer drug maker Peloton Therapeutics for $1.05Bn
  Author: Mateen Dalal

The acquisition would help Merck strengthen its presence in the renal cell carcinoma space and support its cancer drug portfolio. U.S. pharmaceutical conglomerate, ...

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BioXcel unveils data from Phase 1 study of receptor agonist BXCL501
  Author: Mateen Dalal

Sublingual administration of BXCL501 had achieved drug exposures that will be therapeutic for the acute treatment of agitation Reports confirm that BioXcel Therapeu...

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Kazia to team up with U.S. oncology group for brain cancer drug trial
  Author: Mateen Dalal

A multi-centre phase-two study will represent the fourth clinical trial ongoing for Kazia’s GDC-0084 drug candidate Kazia Therapeutics Ltd, an Australian onco...

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GSK, Zymeworks expand partnership for bispecific antibody development
  Author: Nikita Chaurasia

GSK anticipates using Zymeworks’ Azymetric technology for developing bispecifics drugs that treat communicable diseases Zymeworks Inc, a clinical-stage biopha...

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Vertex, Kymera join forces for developing protein degradation drugs
  Author: Nikita Chaurasia

Vertex would be paying $70 million in advance to work with Kymera including an equity investment in the company Kymera Therapeutics and Vertex Pharmaceuticals Incor...

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Roche delays acquiring Spark as regulatory review process continues
  Author: Mateen Dalal

Roche, the leading Swiss pharma has pushed back its scheduled acquisition of the gene therapy specialist, Spark Therapeutics for third time in a row, as it waits for the U.S. government to complete regulatory review of...

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Veeba Foods ventures into child nutrition segment with V-Nourish
  Author: Mateen Dalal

Condiments and sauce manufacturer Veeba Foods reportedly ventured into child nutrition segment with a new health beverage, V-Nourish. According to sources close to the matter, V-Nou...

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Pfizer obtains FDA approval for oral heart drug costing $225K a year
  Author: Nikita Chaurasia

In May the drug received FDA breakthrough status and had lowered the risk of death for patients by 30% as compared to placebo The U.S. Food and Drug Administration ...

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Cytokinetics declares FORTITUDE-ALS results from reldesemtiv study
  Author: Nikita Chaurasia

FORTITUDE-ALS did not attain statistical importance in its primary endpoint of change from baseline in SVC Patients who received reldesemtiv in FORTITUDE-AL...

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Context Therapeutics begins Phase 2 Apristor trial for cancer patients
  Author: Mateen Dalal

The latest study will assess Apristor’s safety plus pharmacological profile in patients, besides the biomarker analyses, for exploring the drug’s predictive response factors. ...

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Audentes exhibits new positive data from the ASPIRO clinical trial
  Author: Mateen Dalal

The leading American AAV-based genetic medicines company, Audentes Therapeutics Inc., has reportedly presented new positive data from ASPIRO, the AT132 Phase 1/2 clinical trial for the treatment of XLMTM (X-linked Myot...

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Norton Healthcare & Select Medical tie up on outpatient rehabilitation
  Author: Nikita Chaurasia

In a recent turn of events, Norton Healthcare and Select Medical have reportedly declared signing a joint venture agreement intended to assimilate outpatient rehabilitation solutions in the Southern Indiana and Louisville metro provinces. ...

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Oxurion & Bicycle Therapeutics declare full enrollment for DME study
  Author: Nikita Chaurasia

Bicycle Therapeutics, a biotech firm pioneering a new therapeutic class based on its patented bicyclic peptide or Bicycle® platform, and Oxurion have recently declared complete registration of Oxurion’s Phase...

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Precision BioSciences doses first patient in CAR T cell therapy trial
  Author: Nikita Chaurasia

Precision is creating PBCAR0191 in partnership with Servier, a multinational pharmaceutical firm   The company believes that the patien...

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BioTime to present OpRegen® Phase I/IIa study outcomes at ARVO 2019
  Author: Nikita Chaurasia

BioTime Incorporation, a clinical stage biotechnology firm developing newfangled cellular treatments, has recently declared that updated outcomes from a Phase I/IIa clinical study of OpRegen®, its chief product can...

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FDA approves Gelesis prescription weight-loss drug Plenity for adults
  Author: Mateen Dalal

Plenity is has been cleared for obese or overweight adults having a body mass index of at least 25 Reports confirm that the U.S. Food and Drug Administration (FDA) ...

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Assembly Biosciences reveals data from Phase 2a studies of ABI-H0731
  Author: Mateen Dalal

The data received to date is directionally correct and reduction in HBeAg and HBsAg have been observed in some individuals in both studies. U.S. based clinical-stag...

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Inscripta raises additional $20 million in Series C financing round
  Author: Nikita Chaurasia

Inscripta is working to develop a full suite of gene-editing tools (reagents, software and instruments) to increase the efficiency and speed of CRISPR-based gene-editing ...

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Cyclacel unveils Phase 1 clinical data for its breast cancer treatment
  Author: Mateen Dalal

·         The data was presented at the American Association for Cancer Research Annual Meeting 2019 ·  ...

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Imvax unveils positive results from clinical trial of IGV-001 vaccine
  Author: Nikita Chaurasia

Clinical-stage biotechnology company Imvax, Inc., committed to creating novel patient-specific vaccines and immunotherapy strategies, has reportedly attained positive results from an ongoing Phase 1b clinical trial tha...

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Partners HealthCare to fully integrate its EHR system with MassPAT
  Author: Mateen Dalal

Partners Healthcare has now become the first healthcare network to have the tool immediately available to doctors at the point-of-care in Massachusetts. Partners He...

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Biogen to wholly acquire gene therapy firm Nightstar Therapeutics
  Author: Mateen Dalal

Nightstar’s agreement with Biogen will give the company the platform and resources it needs to expand its mission to restore sight in patients with inherited retinal diseases. ...

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Merck offers $5-9B for Versum Materials to challenge bid from Entegris
  Author: Mateen Dalal

The company is apparently looking to buy the electronic materials maker for bolstering its Performance Materials division Merck KGaA, the laboratory supplies provid...

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